| Literature DB >> 7226133 |
G R Russell, C J Nader, E J Partick.
Abstract
Selenium compounds were found to induce DNA repair synthesis as a measure of DNA damage in both the isolated rat liver cell system and by Ames' Salmonella assay. In liver cells, DNA repair measured by uptake of [3H]thymidine was found to be greater with sodium selenite and selenate than with selenomethionine. In the bacterial culture system, selenomethionine inhibited the repair-deficient variant more than the selenite and selenate. These in vitro test systems have been used to indicate that selenium has a DNA-damaging potential.Entities:
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Year: 1980 PMID： 7226133 DOI： 10.1016/0304-3835(80)90068-3
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679