Literature DB >> 7225916

Methohexitone or etomidate for induction of dental anaesthesia.

H Boralessa, A Holdcroft.   

Abstract

Ninety-two patients who presented for outpatient dental extractions received methohexitone (1.5 mg . kg-1, 46 patients) or etomidate (0.3 mg . kg-1, 23 patients and 0.2 mg . kg-1, 23 patients). The induction characteristics of both drugs such as pain on injection, involuntary muscle movements and respiratory difficulties were comparable and the theoretical disadvantages of etomidate for dental anaesthetics did not prove troublesome in practice. Muscle movements did not interfere with the dentists' manipulations and pain on injection into veins of the antecubital fossa did not occur. The duration of operation for up to four extractions was three minutes and, following induction, anaesthesia was maintained with nitrous oxide, oxygen and halothane. Recovery was assessed by grading consciousness, airway control and motor activity. All the patients could maintain their airways one minute after the end of operation. The incidence of nausea and vomiting was significantly greater in the etomidate group.

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Year:  1980        PMID: 7225916     DOI: 10.1007/bf03006891

Source DB:  PubMed          Journal:  Can Anaesth Soc J        ISSN: 0008-2856


  16 in total

1.  Effect of dose and premedication on induction complications with etomidate.

Authors:  A Holdcroft; M Morgan; J G Whitwam; J Lumley
Journal:  Br J Anaesth       Date:  1976-03       Impact factor: 9.166

2.  Histamine release after intravenous application of short-acting hypnotics. A comparison of etomidate, Althesin (CT1341) and propanidid.

Authors:  A Doenicke; W Lorenz; R Beigl; H Bezecny; G Uhlig; L Kalmar; B Praetorius; G Mann
Journal:  Br J Anaesth       Date:  1973-11       Impact factor: 9.166

3.  Use of methohexitone, fentanyl and nitrous oxide for short surgical procedures.

Authors:  T Goroszeniuk; J G Whitwam; M Morgan
Journal:  Anaesthesia       Date:  1977-02       Impact factor: 6.955

Review 4.  Methohexitone.

Authors:  J G Whitwam
Journal:  Br J Anaesth       Date:  1976-07       Impact factor: 9.166

5.  Evaluation of three preparations of etomidate.

Authors:  M Zacharias; R S Clarke; J W Dundee; S B Johnston
Journal:  Br J Anaesth       Date:  1978-09       Impact factor: 9.166

6.  A dose-response relationship for etomidate, with some observations on cumulation.

Authors:  B Kay
Journal:  Br J Anaesth       Date:  1976-03       Impact factor: 9.166

7.  A clinical assessment of the use of etomidate in children.

Authors:  B Kay
Journal:  Br J Anaesth       Date:  1976-03       Impact factor: 9.166

8.  Pharmacokinetics of methohexitone following intravenous infusion in humans.

Authors:  D D Breimer
Journal:  Br J Anaesth       Date:  1976-07       Impact factor: 9.166

9.  Etomidate in a new solvent. A clinical evaluation.

Authors:  J G Hendry; B M Miller; N W Lees
Journal:  Anaesthesia       Date:  1977 Nov-Dec       Impact factor: 6.955

10.  Effect of preanaesthetic medication on etomidate.

Authors:  M Zacharias; J W Dundee; R S Clarke; J E Hegarty
Journal:  Br J Anaesth       Date:  1979-02       Impact factor: 9.166

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  2 in total

1.  General anesthetics: a comparative review of pharmacodynamics.

Authors:  S B Milam
Journal:  Anesth Prog       Date:  1984 May-Jun

Review 2.  Adverse effects of general anaesthetics.

Authors:  M C Berthoud; C S Reilly
Journal:  Drug Saf       Date:  1992 Nov-Dec       Impact factor: 5.606

  2 in total

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