Literature DB >> 7225822

Regional distribution of [3H]imipramine binding in rat brain.

M Palkovits, R Raisman, M Briley, S Z Langer.   

Abstract

[3H]imipramine binding was measured in 23 microdissected areas of the rat brain and compared to published values for the endogenous levels of serotonin, noradrenaline and dopamine in the same areas. The density of [3H]imipramine binding sites appears to be highly correlated with the distribution of endogenous serotonin especially where the serotonin is located mainly in nerve terminals. A weak but still significant correlation also exists with the distribution of endogenous noradrenaline whereas no such correlation could be detected for endogenous dopamine.

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Year:  1981        PMID： 7225822     DOI： 10.1016/0006-8993(81)90933-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  11 in total

1.  Molecular mechanisms in the action of imipramine.

Authors:  E Costa; D M Chuang; M L Barbaccia; O Gandolfi
Journal:  Experientia       Date:  1983-08-15

2.  Sex differences in long-term gonadectomized rats: monoamine levels and [3H]nitroimipramine binding in brain nuclei.

Authors:  K J Renner; A Biegon; V N Luine
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

3.  High affinity [3H]imipramine and [3H]paroxetine binding sites in suicide brains.

Authors:  P Rosel; B Arranz; J Vallejo; M Oros; J M Menchón; P Alvarez; M A Navarro
Journal:  J Neural Transm (Vienna)       Date:  1997       Impact factor: 3.575

4.  Regional distribution of specific high affinity binding sites for 3H-imipramine and 3H-paroxetine in human brain.

Authors:  P Rosel; J M Menchon; M Oros; J Vallejo; T Cortadellas; B Arranz; P Alvarez; M A Navarro
Journal:  J Neural Transm (Vienna)       Date:  1997       Impact factor: 3.575

5.  Characterization of the monoamine carrier of chromaffin granule membrane by binding of [2-3H]dihydrotetrabenazine.

Authors:  D Scherman; P Jaudon; J P Henry
Journal:  Proc Natl Acad Sci U S A       Date:  1983-01       Impact factor: 11.205

6.  Norepinephrine neuronal uptake binding sites in rat brain membranes labeled with [3H]desipramine.

Authors:  C M Lee; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

Review 7.  Genetic and environmental influences on behavioral and neurochemical aspects of emotionality in rats.

Authors:  C Gentsch; M Lichtsteiner; H Feer
Journal:  Experientia       Date:  1988-06-15

8.  3H-imipramine binding and serotonin uptake in platelets from untreated depressed patients and control volunteers.

Authors:  R Raisman; M S Briley; F Bouchami; D Sechter; E Zarifian; S Z Langer
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

9.  Selective effects of thiol reagents on the binding sites for imipramine and neurotransmitter amines in the rat brain.

Authors:  R Biassoni; A Vaccari
Journal:  Br J Pharmacol       Date:  1985-06       Impact factor: 8.739

10.  High-affinity 3H-imipramine binding in platelets from untreated and treated depressed patients compared to healthy volunteers.

Authors:  R Raisman; D Sechter; M S Briley; E Zarifian; S Z Langer
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530
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