Literature DB >> 7225821

Anesthetics and the habenulo-interpeduncular system: selective sparing of metabolic activity.

M Herkenham.   

Abstract

The method of regional localization of brain metabolism by [14C]deoxyglucose during anesthesia in rats shows that pentobarbital, ether and chloral hydrate reduce deoxyglucose uptake in most neuronal regions, with one common exception: spared or increased metabolism is found in the medial habenula, the interpeduncular nucleus, and the habenulo-interpeduncular tract. Prior destruction of afferent inputs abolishes the selective metabolic sparing in the habenulo-interpeduncular system during chloral hydrate anesthesia.

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Year:  1981        PMID： 7225821     DOI： 10.1016/0006-8993(81)90927-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  11 in total

1.  Loss of Goosecoid-like and DiGeorge syndrome critical region 14 in interpeduncular nucleus results in altered regulation of rapid eye movement sleep.

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2.  Total number of neurons in the habenular nuclei of the rat epithalamus: a stereological study.

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3.  Hearing and memory in anaesthetised patients.

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4.  Projections between the interpeduncular nucleus and basal forebrain in the rat as demonstrated by the anterograde and retrograde transport of WGA-HRP.

Authors:  R P Vertes; B Fass
Journal:  Exp Brain Res       Date:  1988       Impact factor: 1.972

Review 5.  The habenula: from stress evasion to value-based decision-making.

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6.  The Role of the Habenula in Nicotine Addiction.

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7.  Manganese-Enhanced MRI Reflects Both Activity-Independent and Activity-Dependent Uptake within the Rat Habenulomesencephalic Pathway.

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8.  Affective and cognitive prefrontal cortex projections to the lateral habenula in humans.

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9.  Sensitivity to Sevoflurane anesthesia is decreased in mice with a congenital deletion of Guanylyl Cyclase-1 alpha.

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Review 10.  The role of the habenula in drug addiction.

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