Ultrastructure of N-diethylnitrosamine induced tumours in the nasal olfactory region of the Syrian golden hamster.

Tumours of the nasal olfactory region induced in five Syrian golden hamsters ater s.c. treatment with N-diethylnitrosamine (DEN) were examined electron microscopically. The neoplasms consisted of two cell types, the ultrastructure of which showed them to have originated from the precursors of olfactory sensory cells (neuroblasts) and the precursors of sustentacular cells (basal cells).