Literature DB >> 7222043

Dichloroacetate, sodium: 3-month oral toxicity studies in rats and dogs.

R Katz, C N Tai, R M Diener, R F McConnell, D E Semonick.   

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Year:  1981        PMID： 7222043     DOI： 10.1016/0041-008x(81)90289-1

Source DB:  PubMed          Journal:  Toxicol Appl Pharmacol        ISSN： 0041-008X            Impact factor:   4.219


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  8 in total

1.  Treatment of chronic congenital lactic acidosis by oral administration of dichloroacetate.

Authors:  Y Kuroda; M Ito; K Toshima; E Takeda; E Naito; T J Hwang; T Hashimoto; M Miyao; M Masuda; K Yamashita
Journal:  J Inherit Metab Dis       Date:  1986       Impact factor: 4.982

2.  Dichloroacetate attenuates neuronal damage in a gerbil model of brain ischemia.

Authors:  R V Dimlich; P J Marangos
Journal:  J Mol Neurosci       Date:  1994       Impact factor: 3.444

3.  Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.

Authors:  Robert T Wicks; Javad Azadi; Antonella Mangraviti; Irma Zhang; Lee Hwang; Avadhut Joshi; Hansen Bow; Marianne Hutt-Cabezas; Kristin L Martin; Michelle A Rudek; Ming Zhao; Henry Brem; Betty M Tyler
Journal:  Neuro Oncol       Date:  2014-07-22       Impact factor: 12.300

4.  Regulation of rat liver hydroxymethylglutaryl coenzyme A reductase by a new class of noncompetitive inhibitors. Effects of dichloroacetate and related carboxylic acids on enzyme activity.

Authors:  P W Stacpoole; H J Harwood; C E Varnado
Journal:  J Clin Invest       Date:  1983-11       Impact factor: 14.808

5.  Peripheral neuropathy in rats exposed to dichloroacetate.

Authors:  Nigel A Calcutt; Veronica L Lopez; Arjel D Bautista; Leah M Mizisin; Brenda R Torres; Albert L Shroads; Andrew P Mizisin; Peter W Stacpoole
Journal:  J Neuropathol Exp Neurol       Date:  2009-09       Impact factor: 3.685

Review 6.  Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.

Authors:  R J Bull
Journal:  Environ Health Perspect       Date:  2000-05       Impact factor: 9.031

Review 7.  Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?

Authors:  Wen Zhang; Shao-Lin Zhang; Xiaohui Hu; Kin Yip Tam
Journal:  Int J Biol Sci       Date:  2015-11-01       Impact factor: 6.580

8.  Dichloroacetic acid-induced testicular toxicity in male rats and the protective effect of date fruit extract.

Authors:  Amira El Arem; Lamia Lahouar; Emna Behija Saafi; Amira Thouri; Fatma Ghrairi; Zohra Houas; Fadoua Neffati; Lotfi Achour
Journal:  BMC Pharmacol Toxicol       Date:  2017-04-22       Impact factor: 2.483
  8 in total

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