Literature DB >> 7220684

[Morphology of the orbitofrontal cortex in persons schizophrenic psychotics. A Golgi and electron microscopy study].

D Senitz, E Winkelmann.   

Abstract

By employing Golgi's method it is possible to demonstrate the whole neuron with all structural details in the brain of adults. In the orbitofrontal cortex of deceased persons with schizophrenic psychoses the following morphological findings can be obtained which are not demonstrable by other methods: 1. Mainly pyramidal cells with thick and partly sinuous main dendrites which suggest the presence of an increase in spines. 2. Irregularly arranged triangular cells in the lamina VI with thickened dendrites and increased density of spines. 3. Splitting of the myelin lamellae and deposits of various origins and structures. These findings can be interpreted as a possible expression of a changed function.

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Year:  1981        PMID: 7220684

Source DB:  PubMed          Journal:  Psychiatr Neurol Med Psychol (Leipz)        ISSN: 0033-2739


  4 in total

1.  Prenatal disturbances of nerve cell migration in the entorhinal region: a common vulnerability factor in functional psychoses?

Authors:  H Beckmann; H Jakob
Journal:  J Neural Transm Gen Sect       Date:  1991

Review 2.  Oxidative damage and schizophrenia: an overview of the evidence and its therapeutic implications.

Authors:  J K Yao; R D Reddy; D P van Kammen
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

Review 3.  Circumscribed malformation and nerve cell alterations in the entorhinal cortex of schizophrenics. Pathogenetic and clinical aspects.

Authors:  H Jakob; H Beckmann
Journal:  J Neural Transm Gen Sect       Date:  1994

Review 4.  The development concept of "endogenous psychoses".

Authors:  Helmut Beckmann; Hermann Jakob; Dieter Senitz
Journal:  Dialogues Clin Neurosci       Date:  2006       Impact factor: 5.986

  4 in total

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