Literature DB >> 7219910

Sperm penetration assay: useful test in evaluation of male fertility.

L E Karp, R A Williamson, D E Moore, K K Shy, S R Plymate, W D Smith.   

Abstract

The recently developed sperm penetration assay (SPA) tests the functional capacity of sperm. It is based upon the ability of in vitro capacitated human spermatozoa to penetrate zona-free hamster eggs in vitro. The SPA was superior to seminal fluid analysis in predicting both fertility and infertility; in the prediction of infertility, the difference was highly significant. Data further indicated that fertility in the male may not remain constant with the passage of time. The SPA would appear to have wide application both clinically and experimentally.

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Year:  1981        PMID: 7219910

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  5 in total

1.  Treatment of severe male-factor infertility with high concentrations of motile sperm by microinsemination in embryo cryopreservation straws.

Authors:  D G Hammitt; D L Walker; C H Syrop; T M Miller; M R Bennett
Journal:  J In Vitro Fert Embryo Transf       Date:  1991-04

2.  The correlation of sperm chromatin decondensation following in vitro exposure to heparin and sperm penetration rates.

Authors:  D T Carrell; B R Emery; C M Peterson
Journal:  J Assist Reprod Genet       Date:  1998-10       Impact factor: 3.412

3.  Reinitiation of sperm production in gonadotropin-suppressed normal men by administration of follicle-stimulating hormone.

Authors:  A M Matsumoto; A E Karpas; C A Paulsen; W J Bremner
Journal:  J Clin Invest       Date:  1983-09       Impact factor: 14.808

4.  Sulfasalazine-induced abnormal sperm penetration assay reversed on changing to 5-aminosalicylic acid enemas.

Authors:  M Chatzinoff; J M Guarino; S L Corson; F R Batzer; L S Friedman
Journal:  Dig Dis Sci       Date:  1988-01       Impact factor: 3.199

Review 5.  Potential reproductive and postnatal morbidity from exposure to polychlorinated biphenyls: epidemiologic considerations.

Authors:  W J Rogan; B C Gladen; A J Wilcox
Journal:  Environ Health Perspect       Date:  1985-05       Impact factor: 9.031

  5 in total

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