Literature DB >> 7219891

Chemically defined medium enhances bioelectric activity in mouse spinal cord-dorsal root ganglion cultures.

A M Habets, R E Baker, E Brenner, H J Romijn.   

Abstract

Co-cultures of mouse spinal cord with dorsal root ganglion (DRG) cultures were grown either in horse serum (HS)-supplemented medium or in a serum-free, chemically defined medium (CDM). The cytoarchitecture of cord--DRG explants was fully retained in CDM, with little or no distortion due to flattening of the explant, as is invariably observed in HS-supplemented cultures. Functional properties such as bioelectric activity and DRG--spinal cord interconnectivity were well sustained in CDM.

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Year:  1981        PMID： 7219891     DOI： 10.1016/0304-3940(81)90284-6

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  4 in total

1.  Growth and myelination of explant cultures in defined medium.

Authors:  W J Hendelman; N de Savigny; K C Marshall
Journal:  In Vitro Cell Dev Biol       Date:  1985-02

2.  Regional specificity of functional sensory connections in developing spinal cord cultures varies with the incidence of spontaneous bioelectric activity.

Authors:  M A Corner; R E Baker; A M M C Habets
Journal:  Rouxs Arch Dev Biol       Date:  1987-09

3.  Bioelectric activity is required for regional specificity of sensory ganglion projections to spinal cord explants cultured in vitro.

Authors:  M A Corner; A M M C Habets; R E Baker
Journal:  Rouxs Arch Dev Biol       Date:  1987-02

4.  Central neuronal responsiveness to sensory ganglion stimulation is correlated with the incidence of spontaneous bioelectric activity in developing spinal cord cultures.

Authors:  M A Corner; R E Baker
Journal:  Pflugers Arch       Date:  1987-11       Impact factor: 3.657
  4 in total

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