Literature DB >> 7219432

Relationship between DNA damage and survival in formaldehyde-treated mouse cells.

W E Ross, N Shipley.   

Abstract

Mouse cells exposed to formaldehyde (FA) were examined for colony-forming ability and DNA synthesis as well as the induction of DNA damage. Cell survival was unaffected until the FA concentration exceeded 150 microM after which there was an exponential decay in survival. Formaldehyde-treated cells studied by the DNA-alkaline-elution technique exhibited a low frequency of single-strand breaks but extensive DNA-protein crosslinking. These crosslinks were repaired following removal of the drug. The DNA damage was accompanied by inhibition of DNA synthesis.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7219432     DOI： 10.1016/0165-1218(80)90075-0

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  8 in total

1.  DNA-protein crosslinks and p53 protein expression in relation to occupational exposure to formaldehyde.

Authors:  J Shaham; Y Bomstein; R Gurvich; M Rashkovsky; Z Kaufman
Journal:  Occup Environ Med       Date:  2003-06       Impact factor: 4.402

2.  Comparative studies of DNA cross-linking reactions following methylene dimethanesulphonate and its hydrolytic product, formaldehyde.

Authors:  P M O'Connor; B W Fox
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

Review 3.  Experimental toxicology of formaldehyde.

Authors:  H M Bolt
Journal:  J Cancer Res Clin Oncol       Date:  1987       Impact factor: 4.553

4.  Depletion of nasal mucosal glutathione by acrolein and enhancement of formaldehyde-induced DNA-protein cross-linking by simultaneous exposure to acrolein.

Authors:  C W Lam; M Casanova; H D Heck
Journal:  Arch Toxicol       Date:  1985-12       Impact factor: 5.153

5.  Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer.

Authors:  Chun-Chin Chen; Weiran Feng; Pei Xin Lim; Elizabeth M Kass; Maria Jasin
Journal:  Annu Rev Cancer Biol       Date:  2017-12-01

6.  Formation and repair of DNA lesions in kidneys of male mice after acute exposure to methyl chloride.

Authors:  C Ristau; H M Bolt; R R Vangala
Journal:  Arch Toxicol       Date:  1990       Impact factor: 5.153

7.  Contribution of formaldehyde to respiratory cancer.

Authors:  N Nelson; R J Levine; R E Albert; A E Blair; R A Griesemer; P J Landrigan; L T Stayner; J A Swenberg
Journal:  Environ Health Perspect       Date:  1986-12       Impact factor: 9.031

8.  Report on the Consensus Workshop on Formaldehyde.

Authors: 
Journal:  Environ Health Perspect       Date:  1984-12       Impact factor: 9.031
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.