Literature DB >> 7217804

A computer-assisted image-processing system for the analysis of autoradiographs of cerebral metabolic activity.

C F Goochee, W S Rasband, L Sokoloff.   

Abstract

A computerized image-processing system has been developed for quantitative analyses of the autoradiographs obtained with the [14C]deoxyglucose method. By means of this system, these cerebral metabolic images can be digitized and the resultant data can be manipulated for image construction, enhancement, enlargement, and microdensitometric analysis. It is also possible to generate quantitative color-coded metabolic maps that display the distribution of the actual rates of local glucose utilization throughout the entire central nervous system with a resolution conservatively estimated to be equivalent to that of a full-width-half-maximum of approximately 100 micron.

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Year:  1980        PMID： 7217804     DOI： 10.1007/bf02222459

Source DB:  PubMed          Journal:  J Med Syst        ISSN： 0148-5598            Impact factor:   4.460


  10 in total

1.  Local cerebral glucose utilization in the normal conscious macaque monkey.

Authors:  C Kennedy; O Sakurada; M Shinohara; J Jehle; L Sokoloff
Journal:  Ann Neurol       Date:  1978-10       Impact factor: 10.422

2.  Monochrome digital image enhancement.

Authors:  H C Andrews
Journal:  Appl Opt       Date:  1976-02-01       Impact factor: 1.980

3.  The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.

Authors:  L Sokoloff; M Reivich; C Kennedy; M H Des Rosiers; C S Patlak; K D Pettigrew; O Sakurada; M Shinohara
Journal:  J Neurochem       Date:  1977-05       Impact factor: 5.372

4.  Metabolic anatomy of focal motor seizures.

Authors:  R C Collins; C Kennedy; L Sokoloff; F Plum
Journal:  Arch Neurol       Date:  1976-08

5.  The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man.

Authors:  M Reivich; D Kuhl; A Wolf; J Greenberg; M Phelps; T Ido; V Casella; J Fowler; E Hoffman; A Alavi; P Som; L Sokoloff
Journal:  Circ Res       Date:  1979-01       Impact factor: 17.367

6.  Computerized densitometry and color coding of [14C] deoxyglucose autoradiographs.

Authors:  C Goochee; W Rasband; L Sokoloff
Journal:  Ann Neurol       Date:  1980-04       Impact factor: 10.422

Review 7.  Relation between physiological function and energy metabolism in the central nervous system.

Authors:  L Sokoloff
Journal:  J Neurochem       Date:  1977-07       Impact factor: 5.372

8.  Brain function and blood flow.

Authors:  N A Lassen; D H Ingvar; E Skinhøj
Journal:  Sci Am       Date:  1978-10       Impact factor: 2.142

9.  Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: validation of method.

Authors:  M E Phelps; S C Huang; E J Hoffman; C Selin; L Sokoloff; D E Kuhl
Journal:  Ann Neurol       Date:  1979-11       Impact factor: 10.422

10.  Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic [14C]deoxyglucose technique.

Authors:  C Kennedy; M H Des Rosiers; O Sakurada; M Shinohara; M Reivich; J W Jehle; L Sokoloff
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205
  10 in total
  1 in total

1.  Effect of Intranasally Delivered rh-VEGF165 on Angiogenesis Following Cerebral Hypoxia-Ischemia in the Cerebral Cortex of Newborn Piglets.

Authors:  Amit Jain; Panagiotis Kratimenos; Ioannis Koutroulis; Amishi Jain; Amulya Buddhavarapu; Jahan Ara
Journal:  Int J Mol Sci       Date:  2017-11-07       Impact factor: 5.923
  1 in total

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