| Literature DB >> 7216418 |
R T Cursons, T J Brown, E A Keys, K M Moriarty, D Till.
Abstract
Pathogenic free-living amoebae are common in nature, but few clinical infections by these amoebae have been reported. This has prompted studies of host susceptibility factors in humans. A survey of normal human sera from three New Zealand Health Districts was made; antibodies to pathogenic free-living amoebae were found in all sera, with titers ranging from 1:5 to 1:20 for Naegleria spp. and from 1:20 to 1:80 for Acanthamoeba spp. The antibodies belonged mainly to immunoglobulin G and immunoglobulin M classes. The presence of a specific neutralizing factor against Acanthamoeba spp. but not Naegleria spp. was demonstrated. Possible protective mechanisms are discussed.Entities:
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Year: 1980 PMID： 7216418 PMCID： PMC551132 DOI： 10.1128/iai.29.2.401-407.1980
Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441