Literature DB >> 7215437

The nucleus reticularis lateralis: a region highly sensitive to clonidine.

P Bousquet, J Feldman, R Bloch, J Schwartz.   

Abstract

Slow bilateral microinjections of a low dose of clonidine (75 ng/kg) in the cat's nucleus reticularis lateralis (NRL) lead to significant hypotension and bradycardia. This finding confirms the existence of a ventromedullary highly sensitive site of action of clonidine. It is suggested that clonidine inhibits some vasopressive and cardioacceleratory structures within the NRL region.

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Year:  1981        PMID： 7215437     DOI： 10.1016/0014-2999(81)90490-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  12 in total

1.  Respective contributions of alpha-adrenergic and non-adrenergic mechanisms in the hypotensive effect of imidazoline-like drugs.

Authors:  V Bruban; J Feldman; H Greney; M Dontenwill; S Schann; C Jarry; M Payard; J Boutin; E Scalbert; B Pfeiffer; P Renard; P Vanhoutte; P Bousquet
Journal:  Br J Pharmacol       Date:  2001-05       Impact factor: 8.739

Review 2.  Drugs acting on imidazoline receptors: a review of their pharmacology, their use in blood pressure control and their potential interest in cardioprotection.

Authors:  P Bousquet; J Feldman
Journal:  Drugs       Date:  1999-11       Impact factor: 9.546

3.  Noradrenergic modulation of the medullary respiratory rhythm generator in the newborn rat: an in vitro study.

Authors:  S Errchidi; R Monteau; G Hilaire
Journal:  J Physiol       Date:  1991-11       Impact factor: 5.182

4.  Centrally acting imidazolines stimulate vascular alpha 1A-adrenergic receptors in Rat-Tail Artery.

Authors:  Wentsworth B Kennedy; Louis Crane; Ramon R Gonzalez; Oommen K George; Lincoln P Edwards
Journal:  Cell Mol Neurobiol       Date:  2006-08-02       Impact factor: 5.046

5.  Cardiovascular effects of rilmenidine, moxonidine and clonidine in conscious wild-type and D79N alpha2A-adrenoceptor transgenic mice.

Authors:  Q M Zhu; J D Lesnick; J R Jasper; S J MacLennan; M P Dillon; R M Eglen; D R Blue
Journal:  Br J Pharmacol       Date:  1999-03       Impact factor: 8.739

6.  Evidence for the involvement of imidazoline receptors in the central hypotensive effect of rilmenidine in the rabbit.

Authors:  J Feldman; E Tibiriça; G Bricca; M Dontenwill; A Belcourt; P Bousquet
Journal:  Br J Pharmacol       Date:  1990-07       Impact factor: 8.739

7.  An analysis of the alpha-adrenoceptor modulation of vasomotor tone at the level of lateral medullary pressor area (LMPA).

Authors:  J N Sinha; S Gurtu; D K Sharma; K P Bhargava
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-09       Impact factor: 3.000

8.  Relevance of the use of [3H]-clonidine to identify imidazoline receptors in the rabbit brainstem.

Authors:  G Bricca; J Zhang; H Greney; M Dontenwill; J Stutzmann; A Belcourt; P Bousquet
Journal:  Br J Pharmacol       Date:  1993-12       Impact factor: 8.739

9.  Sympathoinhibitory effects of rilmenidine may be mediated by sites located below the brainstem.

Authors:  F Sannajust; C Barrès; E Koenig-Bérard; J Sassard
Journal:  Br J Pharmacol       Date:  1992-03       Impact factor: 8.739

10.  A comparative study of the reversal by different alpha 2-adrenoceptor antagonists of the central sympatho-inhibitory effect of clonidine.

Authors:  C Vayssettes-Courchay; F Bouysset; A A Cordi; M Laubie; T J Verbeuren
Journal:  Br J Pharmacol       Date:  1996-02       Impact factor: 8.739
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