Literature DB >> 721315

Stimulation of human NK-cell activity by cultured cells. I. Response of normals.

P Grohmann, W Holmes, F Porzsolt, I Quirt, R G Miller, R A Phillips.   

Abstract

Natural cell-mediated cytotoxicity, observed on co-cultivation of peripheral blood lymphocytes (PBL) with malignant melanoma tumor cells (M4), is described. The activity was inhibited when PBL were cultured in autologous serum. Studies using competitive inhibition with cold targets and stimulation of PBL with other tumor cell lines failed to detect specificity.

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Year:  1978        PMID： 721315     DOI： 10.1002/ijc.2910220504

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  2 in total

1.  Deficient natural killer cell activity in a patient with Fanconi's anaemia and squamous cell carcinoma. Association with defect in interferon release.

Authors:  P Hersey; A Edwards; R Lewis; A Kemp; J McInnes
Journal:  Clin Exp Immunol       Date:  1982-04       Impact factor: 4.330

2.  Stimulation of human NK cell activity by cultured cells. II Ingestion of aspirin by blood donors suppresses induced NK activity.

Authors:  P H Grohmann; F Porzsolt; I Quirt; R G Miller; R A Phillips
Journal:  Clin Exp Immunol       Date:  1981-06       Impact factor: 4.330
  2 in total

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