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Literature DB >> 7212417

Inheritance of copper toxicosis in Bedlington terriers.

G F Johnson, I Sternlieb, D C Twedt, P S Grushoff, I Scheinberg.

Abstract

The mode of transmission of copper toxicosis, previously reported to be associated with progressive hepatic disease in certain Bedlington Terriers, has been studied by means of 5 matings involving affected and unaffected Bedlington Terriers and dogs of different breeds. The abnormally large concentration of hepatic copper underlying the disorder was found to follow an autosomal recessive pattern of inheritance.

Entities: Chemical Disease Species

Mesh：

Substances：
Copper

Year: 1980 PMID： 7212417

Source DB: PubMed Journal: Am J Vet Res ISSN： 0002-9645 Impact factor: 1.156

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Cited

11 in total

1. Microsatellite marker C04107 as a diagnostic marker for copper toxicosis in the Danish population of Bedlington terriers.

Authors: H F Proschowsky; B Jepsen; H E Jensen; A L Jensen; M Fredholm
Journal: Acta Vet Scand Date: 2000 Impact factor: 1.695

2. Quantitative PCR method to detect a 13-kb deletion in the MURR1 gene associated with copper toxicosis and HIV-1 replication.

Authors: Robert P Favier; Bart Spee; Louis C Penning; Bas Brinkhof; Jan Rothuizen
Journal: Mamm Genome Date: 2005-06 Impact factor: 2.957

Inheritance of copper toxicosis in Bedlington terriers.

1. Microsatellite marker C04107 as a diagnostic marker for copper toxicosis in the Danish population of Bedlington terriers.

2. Quantitative PCR method to detect a 13-kb deletion in the MURR1 gene associated with copper toxicosis and HIV-1 replication.

3. Prevalence of the exon 2 deletion of the COMMD1 gene in Australian Bedlington terriers.

4. Copper toxicosis in Bedlington Terriers.

5. Inherited copper toxicosis in Bedlington terriers: Wilson's disease (hepatolenticular degeneration).

6. Analysis of the human homologue of the canine copper toxicosis gene MURR1 in Wilson disease patients.

7. New haplotypes in the Bedlington terrier indicate complexity in copper toxicosis.

Review 8. Canine models of copper toxicosis for understanding mammalian copper metabolism.

9. Prevalence and Clinical Relevance of Exon 2 Deletion of COMMD1 in Bedlington Terriers in Korea.

10. Sensitivity and Specificity of Plasma ALT, ALP, and Bile Acids for Hepatitis in Labrador Retrievers.