Literature DB >> 7211963

The estimation of phenotype distributions from pedigree data.

R M Winter.   

Abstract

A method is described to estimate from pedigree data that probability density function of a quantitative phenotype, given a specific genotype. Theoretically, pedigrees of any size or complexity that are segregating for conditions of known Mendelian inheritance can be used. Under certain circumstances, the estimates are unbiased by the method of ascertainment.

Mesh:

Year:  1980        PMID: 7211963     DOI: 10.1002/ajmg.1320070415

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN: 0148-7299


  3 in total

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Authors:  Ola Hössjer
Journal:  J Math Biol       Date:  2004-11-11       Impact factor: 2.259

2.  Classification of Missense Mutations of Disease Genes.

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Journal:  J Am Stat Assoc       Date:  2005       Impact factor: 5.033

3.  A resolution of the ascertainment sampling problem. II. Generalizations and numerical results.

Authors:  N C Shute; W J Ewens
Journal:  Am J Hum Genet       Date:  1988-10       Impact factor: 11.025

  3 in total

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