Literature DB >> 7210698

Metabolism of limonene-1,2-epoxide in the rat.

J W Regan, M M Morris, B Nao, L F Bjeldanes.   

Abstract

1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, p-mentha-2,8-dien-1-alpha and -beta-ol and p-mentha-1,8-dien-6-alpha and -beta-ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.

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Year:  1980        PMID: 7210698     DOI: 10.3109/00498258009033819

Source DB:  PubMed          Journal:  Xenobiotica        ISSN: 0049-8254            Impact factor:   1.908


  1 in total

1.  Identification of metabolites of the antitumor agent d-limonene capable of inhibiting protein isoprenylation and cell growth.

Authors:  P L Crowell; S Lin; E Vedejs; M N Gould
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

  1 in total

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