Literature DB >> 7209554

Drug discrimination learning in lead-exposed rats.

H Zenick, M Goldsmith.   

Abstract

Lead acetate (0.02 or 0.5 percent) was administered to dams throughout the lactation period with half of the litters continuing on lead after weaning. Drug thresholds for d-amphetamine were determined by using the drug-discrimination learning paradigm. All the offspring that had been exposed to lead were less sensitive to the stimulus properties of d-amphetamine irrespective of whether or not they had continued on lead after weaning.

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Year:  1981        PMID： 7209554     DOI： 10.1126/science.7209554

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Neurotoxicity of methamphetamine and methylenedioxymethamphetamine.

Authors:  L S Seiden; R Lew; J E Malberg
Journal:  Neurotox Res       Date:  2001-01       Impact factor: 3.911

2.  Low-dose caffeine discrimination and self-reported mood effects in normal volunteers.

Authors:  K Silverman; R R Griffiths
Journal:  J Exp Anal Behav       Date:  1992-01       Impact factor: 2.468

Review 3.  Trends in drug discrimination research analysed with a cross-indexed bibliography, 1982-1983.

Authors:  I P Stolerman; P J Shine
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

4.  Discriminative stimulus effects of diazepam and buspirone in normal volunteers.

Authors:  C R Rush; T S Critchfield; J R Troisi; R R Griffiths
Journal:  J Exp Anal Behav       Date:  1995-05       Impact factor: 2.468

Review 5.  Drug discrimination by humans compared to nonhumans: current status and future directions.

Authors:  J B Kamien; W K Bickel; J R Hughes; S T Higgins; B J Smith
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

6.  Influence of chronic inorganic lead exposure on regional dopamine and 5-hydroxytryptamine turnover in rat brain.

Authors:  S M Lasley; R D Greenland; D J Minnema; I A Michaelson
Journal:  Neurochem Res       Date:  1984-12       Impact factor: 3.996

7.  Tactile-kinesthetic system of rats as an animal model for minimal brain dysfunction.

Authors:  J Elsner
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

8.  Measurement of the lowest dosage of phenobarbital that can produce drug discrimination in rats.

Authors:  Donald A Overton; Gregg D Stanwood; Bhavesh N Patel; Sreenivasa R Pragada; M Kathleen Gordon
Journal:  Psychopharmacology (Berl)       Date:  2008-12-13       Impact factor: 4.530

9.  Altered central monoamine response to D-amphetamine in rats chronically exposed to inorganic lead.

Authors:  S M Lasley; R D Greenland; D J Minnema; I A Michaelson
Journal:  Neurochem Res       Date:  1985-07       Impact factor: 3.996

10.  Responsiveness to cocaine challenge in adult rats following prenatal exposure to cocaine.

Authors:  C J Heyser; L Rajachandran; N E Spear; L P Spear
Journal:  Psychopharmacology (Berl)       Date:  1994-09       Impact factor: 4.530
  10 in total

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