Literature DB >> 7205386

A shielded synthesis system for production of 2-deoxy-2-[18F]fluoro-D-glucose.

J S Fowler, R R MacGregor, A P Wolf, A A Farrell, K I Karlstrom, T J Ruth.   

Abstract

A remotely operated, shielded synthesis system for the production of 2-deoxy-2-[18F]fluoro-D-glucose (18FDG) for clinical studies has been developed. Using this system, 25 mCi of 18FDG are produced a the end of a 60-min synthesis from approximately 300 mCi of F-18 (total F-18 recovered from the target at the end of bombardment). The fractional distribution of F-18 among various components of the synthesis system has been measured. This yield of 18FDG (25 mCi) is ample for two consecutive human studies in house or for shipment to collaborating institutions within a 3-hr (door to door) radius.

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Year:  1981        PMID: 7205386

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  7 in total

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Journal:  Chem Soc Rev       Date:  2014-10-07       Impact factor: 54.564

Review 3.  Positron emission tomography.

Authors:  Y L Yamamoto; C J Thompson; M Diksic; E Meyer; W H Feindel
Journal:  Neurosurg Rev       Date:  1984       Impact factor: 3.042

4.  Synthesis and biodistribution of 2-deoxy-2-[18F]fluoro-D-glucopyranosyl [18F]fluoride in mice.

Authors:  C Y Shiue; C D Arnett; A P Wolf
Journal:  Eur J Nucl Med       Date:  1984

5.  Production of 18F-labelled 2-deoxy-2-fluoro-D-glucose and preliminary imaging results.

Authors:  G Mestelan; C Crouzel; C Cepeda; J C Baron
Journal:  Eur J Nucl Med       Date:  1982

6.  Experimental study for cancer diagnosis with positron-labeled fluorinated glucose analogs: [18F]-2-fluoro-2-deoxy-D-mannose: a new tracer for cancer detection.

Authors:  H Fukuda; T Matsuzawa; Y Abe; S Endo; K Yamada; K Kubota; J Hatazawa; T Sato; M Ito; T Takahashi; R Iwata; T Ido
Journal:  Eur J Nucl Med       Date:  1982

7.  Synthesis of 2-deoxy-2-[82Br]bromo-D-mannose and related compounds and their biodistributions in mice.

Authors:  Y G Zhou; C Y Shiue; A P Wolf; C D Arnett
Journal:  Eur J Nucl Med       Date:  1985
  7 in total

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