Literature DB >> 72048

Hydroxyethyl starch-induced macroamylasemia.

H Köhler, W Kirch, H J Horstmann.   

Abstract

Summarizing, the following results were obtained: 1. After infusion of 500 ml hydroxyethyl starch 6% in all patients an increase of serum amylase occurred, which in most cases reached values twice as high as the basal value. 2. This hyperamylasemia is caused by the formation of a high molecular HES-amylase complex, which cannot be easily eliminated. 3. In no case was hyperamylasemia associated with other clinical signs or symptoms.

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Year:  1977        PMID: 72048

Source DB:  PubMed          Journal:  Int J Clin Pharmacol Biopharm        ISSN: 0340-0026


  4 in total

1.  Pharmacokinetics and safety of 6 % hydroxyethyl starch 130/0.4 in healthy male volunteers of Japanese ethnicity after single infusion of 500 ml solution.

Authors:  Michiaki Yamakage; Frank Bepperling; Manfred Wargenau; Hideki Miyao
Journal:  J Anesth       Date:  2012-06-23       Impact factor: 2.078

Review 2.  Adverse reactions to plasma volume expanders.

Authors:  M M Fisher; P W Brady
Journal:  Drug Saf       Date:  1990 Mar-Apr       Impact factor: 5.606

Review 3.  Macroamylasemia and other immunoglobulin-complexed enzyme disorders.

Authors:  D C Klonoff
Journal:  West J Med       Date:  1980-11

Review 4.  Use of plasma volume expanders in myocardial revascularisation.

Authors:  J H Lacy; C B Wright
Journal:  Drugs       Date:  1992-11       Impact factor: 9.546

  4 in total

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