Literature DB >> 7203881

Humoral and cellular immunity studies in patients with Vogt-Koyanagi-Harada syndrome and pars planitis.

M M Yokoyama, Y Matsui, H M Yamashiroya, M J O'Donnell, C H Tseng, D A Snyder, H H Tessler, R G Crispen, C M Zimjewski.   

Abstract

We performed a comprehensive immunologic assessment of 17 patients with Vogt-Koyanagi-Harada syndrome (VKH) and nine with pars planitis (PP). Several variations in humoral and cellular immunity were found when the patients were compared with normal controls. Elevated serum IgD levels, positive results from various autoimmune profile assays, and deviations from normal levels of viral antibody titers were noted in both groups of patients. However, only some VKH patients had elevated beta 2 microglobulin, total complement level and E-active and EA rosette counts. HLA haplotype typing revealed no distinct correlation between patients when compared with a normal population.

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Year:  1981        PMID: 7203881

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  6 in total

Review 1.  A clinical and histopathological review of intermediate uveitis ("pars planitis").

Authors:  J W Eichenbaum; A H Friedman; A E Mamelok
Journal:  Bull N Y Acad Med       Date:  1988-03

2.  Clinical and immunopathological studies of pars planitis in a family.

Authors:  R P Wetzig; C C Chan; R B Nussenblatt; A G Palestine; D O Mazur; K K Mittal
Journal:  Br J Ophthalmol       Date:  1988-01       Impact factor: 4.638

3.  Serum and tear immunoglobulin levels in acute adenovirus conjunctivitis.

Authors:  A K Gupta; G S Sarin
Journal:  Br J Ophthalmol       Date:  1983-03       Impact factor: 4.638

4.  HLA-DRB1 among patients with Vogt-Koyanagi-Harada disease in Saudi Arabia.

Authors:  Alia Iqniebi; Ameera Gaafar; Atia Sheereen; Abdullah Al-Suliman; Gamal Mohamed; Khaled Al-Hussein; Khalid F Tabbara
Journal:  Mol Vis       Date:  2009-09-12       Impact factor: 2.367

5.  Immunological studies in patients suffering from sympathetic ophthalmitis.

Authors:  H Hammer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1982       Impact factor: 3.117

Review 6.  Precise, simplified diagnostic criteria and optimised management of initial-onset Vogt-Koyanagi-Harada disease: an updated review.

Authors:  Carl P Herbort; Ilknur Tugal-Tutkun; Ahmed Abu-El-Asrar; Amod Gupta; Masaru Takeuchi; Christine Fardeau; Alireza Hedayatfar; Cristhian Urzua; Ioannis Papasavvas
Journal:  Eye (Lond)       Date:  2021-06-18       Impact factor: 3.775

  6 in total

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