Literature DB >> 7201719

Studies on Escherichia coli vaccines: estimation of endotoxins in veterinary vaccines.

S N Hussaini, R A Ready.   

Abstract

Fifteen batches of E. coli vaccines for pigs, from three different manufacturers, were subjected to a quantitative form of the in vitro Limulus-amoebocyte-lysate (LAL) test for their free endotoxin content. A batch of vaccine associated with abortions in pregnant sows was found to contain a much higher level of free endotoxin than batches of vaccine not associated with abortion. The evidence of these assays suggests that they will be useful in the quality control of E. coli vaccines.

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Year:  1981        PMID： 7201719     DOI： 10.1007/bf02214982

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN： 0165-7380            Impact factor:   2.459


  9 in total

1.  Studies on the mechanisms involved in the production of abortion by endotoxin.

Authors:  R F REIDER; L THOMAS
Journal:  J Immunol       Date:  1960-02       Impact factor: 5.422

2.  The physiological disturbances produced by endotoxins.

Authors:  L THOMAS
Journal:  Annu Rev Physiol       Date:  1954       Impact factor: 19.318

3.  Experimentally induced bacterial endotoxaemia and abortion in pigs.

Authors:  A E Wrathall; C Wray; J Bailey; D E Wells
Journal:  Br Vet J       Date:  1978 May-Jun

4.  Relationship of structure and biological activity of bacterial endotoxins.

Authors:  A Nowotny
Journal:  Naturwissenschaften       Date:  1971-08

5.  Detection of endotoxin in human blood and demonstration of an inhibitor.

Authors:  J Levin; P A Tomasulo; R S Oser
Journal:  J Lab Clin Med       Date:  1970-06

6.  The limulus amebocyte lysate test micromethod and application in the control of sera and vaccines.

Authors:  J G Kreeftenberg; H G Loggen; J D van Ramshorst; E C Beuvery
Journal:  Dev Biol Stand       Date:  1977

7.  Endotoxins in commercial vaccines.

Authors:  M R Geier; H Stanbro; C R Merril
Journal:  Appl Environ Microbiol       Date:  1978-09       Impact factor: 4.792

8.  Studies on the toxicity of a variety of human vaccines as measured by laboratory tests.

Authors:  P A Knight; R N Lucken
Journal:  Dev Biol Stand       Date:  1977

9.  Bacterial endotoxin and impaired fetal development.

Authors:  C R Coid
Journal:  Experientia       Date:  1976-06-15
  9 in total

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