[Results of local transurethral high frequency hyperthermia in bladder carcinoma (author's transl)].

On the basis of controversial results from clinical use of hyperthermal irrigation of the bladder lumen published by various authors a procedure was developed for transurethral local high frequency hyperthermia using phantom experiments and experimental bladder tumors. Encouraging results from experiments on animals led to clinical use of this technique with pretreated recurring bladder tumors (n = 64) at various stages. Poorly differentiated tumors at higher stages responded especially well. Typical pathohistological findings induced by hyperthermia were in these cases extensive tumor-necroses, and as late finding stromahyalinoses. Permanent changes of tumorfree urothelium have not been observed. During the observation period up to the present (maximum 48 month) the 3-year-survival rate has been 92.5% (T1G2-3), 59.4% (T2G3) and 22.0% (T3G3).