| Literature DB >> 7200260 |
S Siegel, R E Hinson, M D Krank, J McCully.
Abstract
A model of "overdose" deaths among heroin addicts is proposed which emphasizes recent findings concerning the contribution of drug-associated environmental cues to drug tolerance. Results of animal experiments performed to evaluate this model suggest that conditioned drug-anticipatory responses, in addition to pharmacological factors, affect heroin-induced mortality.Entities:
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Year: 1982 PMID: 7200260 DOI: 10.1126/science.7200260
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728