Literature DB >> 7199593

Symptomatological classification in the development of stroke in stroke-prone spontaneously hypertensive rats.

Y Yamori, R Horie, I Akiguchi, M Kihara, Y Nara, W Lovenberg.   

Abstract

The developmental course of cerebrovascular diseases was examined by comparative neurological and pathological studies in stroke-prone SHR (SHRSP) which died spontaneously or were sacrificed. Behavioral status during their life span could be simply divided into 4 patterns, i.e., "no abnormalities", "irritable", "lethergic" and "akinetic" named Grades 0, I, II and III, respectively (Yamori's Classification). Grades I, II and III of behavioral status corresponded well to symptomato-pathoanatomically divided 3 stages (relating to brain edema), i.e., Stages I, II and III, respectively.

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Year:  1982        PMID： 7199593     DOI： 10.1253/jcj.46.274

Source DB:  PubMed          Journal:  Jpn Circ J        ISSN： 0047-1828


  4 in total

1.  Intranasal Losartan Decreases Perivascular Beta Amyloid, Inflammation, and the Decline of Neurogenesis in Hypertensive Rats.

Authors:  Henning J Drews; Konstantin Yenkoyan; Ali Lourhmati; Marine Buadze; Daniela Kabisch; Stephan Verleysdonk; Stefan Petschak; Sandra Beer-Hammer; Tigran Davtyan; William H Frey; Christoph H Gleiter; Matthias Schwab; Lusine Danielyan
Journal:  Neurotherapeutics       Date:  2019-07       Impact factor: 7.620

2.  Replacement of salt by a novel potassium- and magnesium-enriched salt alternative improves the cardiovascular effects of ramipril.

Authors:  E M Mervaala; I Paakkari; J Laakso; R Nevala; T M Teräväinen; F Fyhrquist; H Vapaatalo; H Karppanen
Journal:  Br J Pharmacol       Date:  1994-04       Impact factor: 8.739

3.  Improvement of cardiovascular effects of metoprolol by replacement of common salt with a potassium- and magnesium-enriched salt alternative.

Authors:  E M Mervaala; J Laakso; H Vapaatalo; H Karppanen
Journal:  Br J Pharmacol       Date:  1994-06       Impact factor: 8.739

4.  Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats.

Authors:  De-Hua He; Liang-Min Zhang; Li-Ming Lin; Ruo-Bing Ning; Hua-Jun Wang; Chang-Sheng Xu; Jin-Xiu Lin
Journal:  Int J Mol Med       Date:  2013-12-10       Impact factor: 4.101
  4 in total

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