Literature DB >> 7198313

In vitro effects of prostaglandins on the guinea pig detrusor and bladder outlet.

A E Finkbeiner, N K Bissada.   

Abstract

The effects of prostaglandins on the urinary bladder and urethra were determined using guinea pig detrusor and urethral muscle strips in an in vitro muscle bath. Prostaglandins E1, E2, F1a and F2a caused contraction of detrusor strips and relaxation of strips from the bladder outlet. Their mechanism of action appears to be mediated through the sympathetic nervous system in both the detrusor and outlet with some direct relaxation effects in the outlet.

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Year:  1981        PMID： 7198313     DOI： 10.1007/bf00257777

Source DB:  PubMed          Journal:  Urol Res        ISSN： 0300-5623


  29 in total

Review 1.  Current status of the prostaglandins.

Authors:  T O Oesterling
Journal:  Am J Hosp Pharm       Date:  1974-04

Review 2.  Prostaglandins at adrenergic nerve-endings.

Authors:  E W Horton
Journal:  Br Med Bull       Date:  1973-05       Impact factor: 4.291

Review 3.  Prostaglandins and the central nervous system.

Authors:  F Coceani
Journal:  Arch Intern Med       Date:  1974-01

Review 4.  Prostaglandins.

Authors:  J R Weeks
Journal:  Annu Rev Pharmacol       Date:  1972       Impact factor: 13.820

5.  Innervation of the vesical detrusor muscle by the ganglia of the pelvic plexus.

Authors:  W E Bradley; C T Teague
Journal:  Invest Urol       Date:  1968-11

6.  Editorial: The medical significance of prostaglandins.

Authors:  D E Wilson
Journal:  Arch Intern Med       Date:  1974-01

7.  Prostaglandins as therapeutic agents.

Authors:  J Lee; S Wessler; L V Avioli
Journal:  Arch Intern Med       Date:  1973-02

8.  Hormones released into the circulation when the urinary bladder of the anaesthetized dog is distended.

Authors:  N J Gilmore; J R Vane
Journal:  Clin Sci       Date:  1971-07       Impact factor: 6.124

9.  The effect of polyphloretin phosphate on some smooth muscle actions of prostaglandins in the cat.

Authors:  R Villanueva; L Hinds; R L Katz; K E Eakins
Journal:  J Pharmacol Exp Ther       Date:  1972-01       Impact factor: 4.030

10.  Clinical and experimental studies on the action of prostaglandins and their synthesis inhibitors on detrusor muscle in vitro and in vivo.

Authors:  M I Bultitude; N H Hills; K E Shuttleworth
Journal:  Br J Urol       Date:  1976
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  1 in total

1.  International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.

Authors:  Xavier Norel; Yukihiko Sugimoto; Gulsev Ozen; Heba Abdelazeem; Yasmine Amgoud; Amel Bouhadoun; Wesam Bassiouni; Marie Goepp; Salma Mani; Hasanga D Manikpurage; Amira Senbel; Dan Longrois; Akos Heinemann; Chengcan Yao; Lucie H Clapp
Journal:  Pharmacol Rev       Date:  2020-10       Impact factor: 25.468
  1 in total

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