| Literature DB >> 7196024 |
M F Villamil, C Amorena, J Ponce, A Müller, A C Taquini.
Abstract
Changes in blood pressure and body fluids volume caused by an acute saline load were studied in 6 normal and 7 DOCA-salt early hypertensive rats having normal inulin space and plasma volume. After loading, blood pressure increased in the normal group (+23 mm Hg) and fell (-17 mm Hg) in the DOCA-salt group. Expansion of extracellular fluid volume was similar in both groups but expansion of plasma volume was twice as high in the DOCA-salt than in the normal group. The results are compatible with an inhibition of a volume-sensitive vasopressor mechanism possibly involving vasopressin.Entities:
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Year: 1981 PMID： 7196024 DOI： 10.1007/bf00658272
Source DB: PubMed Journal: Pflugers Arch ISSN： 0031-6768 Impact factor: 3.657