Literature DB >> 7194074

Gastroprotective and anti-inflammatory properties of green lipped mussel (Perna canaliculus) preparation.

K D Rainsford, M W Whitehouse.   

Abstract

Freeze-dried powdered preparations of whole (i.e. without shell) green-lipped mussel (Perna canaliculus) from New Zealand given orally to rats showed some modest anti-inflammatory activity (carrageenan paw oedema). This material strikingly reduced the gastric ulcerogenicity of several non-steroid anti-inflammatory drugs in rats and pigs. The gastroprotective activity in rats was primarily associated with particular lipid fractions, which exhibited differential protective activity against acetylsalicylic acid on the one hand and indometacin on the other.

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Year:  1980        PMID： 7194074

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN： 0004-4172


  12 in total

1.  Green-lipped mussel (Perna canaliculus) extract efficacy in knee osteoarthritis and improvement in gastrointestinal dysfunction: a pilot study.

Authors:  Samantha Coulson; Phillip Vecchio; Helen Gramotnev; Luis Vitetta
Journal:  Inflammopharmacology       Date:  2012-02-26       Impact factor: 4.473

Review 2.  Gastric cytoprotection 30 years after its discovery by André Robert: a personal perspective.

Authors:  Gyula Mózsik
Journal:  Inflammopharmacology       Date:  2010-07-02       Impact factor: 4.473

3.  Anti-inflammatory activities of aqueous/ethanol and methanol extracts of Perna viridis Linn. in mice.

Authors:  K L Sreejamole; C K Radhakrishnan; J Padikkala
Journal:  Inflammopharmacology       Date:  2011-02-27       Impact factor: 4.473

4.  Acute gastrointestinal toxic effects of suspensions of unencapsulated and encapsulated ibuprofen in rats.

Authors:  C M Adeyeye; J D Bricker; V D Vilivalam; W I Smith
Journal:  Pharm Res       Date:  1996-05       Impact factor: 4.200

Review 5.  Systematic review of a marine nutriceutical supplement in clinical trials for arthritis: the effectiveness of the New Zealand green-lipped mussel Perna canaliculus.

Authors:  Christopher S Cobb; Edzard Ernst
Journal:  Clin Rheumatol       Date:  2005-10-12       Impact factor: 2.980

6.  Lipid, FA, and sterol composition of New Zealand green lipped mussel (Perna canaliculus) and Tasmanian blue mussel (Mytilus edulis).

Authors:  Karen J Murphy; Ben D Mooney; Neil J Mann; Peter D Nichols; Andrew J Sinclair
Journal:  Lipids       Date:  2002-06       Impact factor: 1.880

7.  Combination anti-inflammatory therapy: synergism in rats of NSAIDs/corticosteroids with some herbal/animal products.

Authors:  M W Whitehouse; D E Butters
Journal:  Inflammopharmacology       Date:  2003       Impact factor: 4.473

8.  Evaluating Complementary Therapies for Canine Osteoarthritis Part I: Green-lipped Mussel (Perna canaliculus).

Authors:  Anna Hielm-Björkman; Riitta-Mari Tulamo; Hanna Salonen; Marja Raekallio
Journal:  Evid Based Complement Alternat Med       Date:  2007-10-29       Impact factor: 2.629

9.  Anti-inflammatory activity of a lipid fraction (lyprinol) from the NZ green-lipped mussel.

Authors:  M W Whitehouse; T A Macrides; N Kalafatis; W H Betts; D R Haynes; J Broadbent
Journal:  Inflammopharmacology       Date:  1997       Impact factor: 5.093

10.  Non-NSAID over-the-counter (OTC) remedies for arthritis: good, bad or indifferent?

Authors:  M W Whitehouse; D E Butters
Journal:  Inflammopharmacology       Date:  1999       Impact factor: 5.093
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