Literature DB >> 719272

Estimation of dissociation constants and relative efficacies of isoprenaline, orciprenaline and terbutaline in guinea-pig isolated atria by use of functional antagonism [proceedings].

K J Broadley, C D Nicholson.   

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Year:  1978        PMID: 719272      PMCID: PMC1668491     

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


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  7 in total

1.  The use of functional antagonism to determine whether beta-adrenoceptor agonists must have a lower efficacy than isoprenaline to be trachea-atria selective in vitro in guinea-pigs.

Authors:  S R O'Donnell; J C Wanstall
Journal:  Br J Pharmacol       Date:  1977-06       Impact factor: 8.739

2.  Differential blockade of guinea-pig atrial rate and force responses to (--)-noradrenaline by practolol - an uptake phenomenon.

Authors:  P Lumley; K J Broadley
Journal:  Eur J Pharmacol       Date:  1975-11       Impact factor: 4.432

3.  Evidence from agonist and antagonist studies to suggest that the beta1-adrenoceptors subserving the positive inotropic and chronotropic responses of the heart do not belong to two separate subgroups.

Authors:  P Lumley; K J Broadley
Journal:  J Pharm Pharmacol       Date:  1977-10       Impact factor: 3.765

4.  Studies on beta-adrenoceptors mediating changes in mechanical events and adenosine 3',5'-monophosphate levels. Rat atria.

Authors:  C K Buckner; T Torphy; D J Costa
Journal:  Eur J Pharmacol       Date:  1978-02-01       Impact factor: 4.432

5.  Evaluation of the cardiac effects of several beta adrenergic blocking agents.

Authors:  J R Blinks
Journal:  Ann N Y Acad Sci       Date:  1967-02-10       Impact factor: 5.691

6.  The model of functional interaction. I. Development and first check of a new model of functional synergism and antagonism.

Authors:  F G van den Brink
Journal:  Eur J Pharmacol       Date:  1973-06       Impact factor: 4.432

Review 7.  Classification and properties of peripheral adrenergic receptors.

Authors:  D H Jenkinson
Journal:  Br Med Bull       Date:  1973-05       Impact factor: 4.291

  7 in total
  2 in total

1.  The determination of receptor constants for histamine H2-agonists in the guinea-pig isolated right atrium using an irreversible H2-antagonist.

Authors:  T J Rising; A Steward
Journal:  Br J Pharmacol       Date:  1986-01       Impact factor: 8.739

2.  Dissociation constants of isoprenaline and orciprenaline and their relative efficacies on guinea-pig isolated atria determined by use of an irreversible beta-adrenoceptor antagonist.

Authors:  K J Broadley; C D Nicholson
Journal:  Br J Pharmacol       Date:  1981-04       Impact factor: 8.739

  2 in total

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