Literature DB >> 7192278

Studies on a new aminoglycoside antibiotic, dactimicin. I. Producing organism and fermentation.

T Shomura, M Kojima, J Yoshida, M Ito, S Amano, K Totsugawa, T Niwa, S Inouye, T Ito, T Niida.   

Abstract

The producing organism of a new antibiotic, dactimicin, is described. The presence of finger-shaped sporangia bearing motile spores, the absence of aerial mycelium and its cell wall of type II, ascribe this organism to the genus Dactylosporangium. The cultural and physiological features distinguish this organism from all the described Dactylosporangium species. Therefore, it is considered to be a new species for which the name Dactylosporangium matsuzakiense sp. nov. is proposed. Fermentation of dactimicin is also described.

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Year:  1980        PMID: 7192278     DOI: 10.7164/antibiotics.33.924

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  7 in total

1.  The ecology of antibiotic production.

Authors:  S T Williams; J C Vickers
Journal:  Microb Ecol       Date:  1986-03       Impact factor: 4.552

2.  Self cloning in Micromonospora olivasterospora of fms genes for fortimicin A (astromicin) biosynthesis.

Authors:  T Dairi; T Ohta; E Hashimoto; M Hasegawa
Journal:  Mol Gen Genet       Date:  1992-03

3.  Dactimicin, a new aminoglycoside: in vitro activity, post-antibiotic effect and interaction with other antibiotics.

Authors:  P Paglia; G Molinari; A Pesce; E A Debbia
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-07       Impact factor: 3.267

4.  Dactylosporangium sucinum sp. nov., isolated from Thai peat swamp forest soil.

Authors:  Wongsakorn Phongsopitanun; Takuji Kudo; Moriya Ohkuma; Khanit Suwanborirux; Somboon Tanasupawat
Journal:  J Antibiot (Tokyo)       Date:  2015-01-21       Impact factor: 2.649

5.  In vitro and in vivo antibacterial activities of dactimicin, a novel pseudodisaccharide aminoglycoside, compared with those of other aminoglycoside antibiotics.

Authors:  Y Matsuhashi; T Yoshida; T Hara; Y Kazuno; S Inouye
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

6.  Organization and nature of fortimicin A (astromicin) biosynthetic genes studied using a cosmid library of Micromonospora olivasterospora DNA.

Authors:  T Dairi; T Ohta; E Hashimoto; M Hasegawa
Journal:  Mol Gen Genet       Date:  1992-12

7.  N-formimidoyl fortimicin A synthase, a unique oxidase involved in fortimicin A biosynthesis: purification, characterization and gene cloning.

Authors:  T Dairi; K Yamaguchi; M Hasegawa
Journal:  Mol Gen Genet       Date:  1992-12
  7 in total

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