Literature DB >> 7189717

DNA and its precursors might interact with the food preservatives, sodium sulphite and sodium benzoate.

G D Njagi, H N Gopalan.   

Abstract

The interaction of sodium sulphite and sodium benzoate with nucleosides and DNA has been studied in vitro. Reduction in UV-absorbance was consistently noticed. However, no new products result from such interaction. It is likely that our previous observations of the effects of the 2 food preservatives on DNA synthesis and mitotis in Vicia faba root meristems is not due to direct action of the chemicals at the level of genetic material.

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Year:  1980        PMID： 7189717     DOI： 10.1007/bf01975120

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Inactivation of valine acceptor ativity by a C-U missense change in the anticodon of yeast valine transfer ribonucleic acid.

Authors:  R W Chambers; S Aoyagi; Y Furukawa; H Zawadzka; O S Bhanot
Journal:  J Biol Chem       Date:  1973-08-10       Impact factor: 5.157

2.  Metabolism and elimination of sulphite by rats, mice and nonkeys.

Authors:  W B Gibson; F M Strong
Journal:  Food Cosmet Toxicol       Date:  1973-04

3.  Bisulfite mutagenesis in bacteriophage T4.

Authors:  G A Summers; J W Drake
Journal:  Genetics       Date:  1971-08       Impact factor: 4.562

4.  The mutagenic action of sodium bisulfite.

Authors:  H Hayatsu; A Miura
Journal:  Biochem Biophys Res Commun       Date:  1970-04-08       Impact factor: 3.575

5.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

Authors:  B N Ames; J Mccann; E Yamasaki
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

6.  [Demonstration of the mutagenic action of sodium sulfite on yeast].

Authors:  J L Dorange; P Dupuy
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1972-05-15

7.  The effects of aqueous salt solutions on the activity coefficients of purine and pyrimidine bases and their relation to the denaturation of deoxyribonucleic acid by salts.

Authors:  D R Robinson; M E Grant
Journal:  J Biol Chem       Date:  1966-09-10       Impact factor: 5.157
  7 in total

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