Literature DB >> 7189514

Corpora amylacea of the optic nerve and retina: a form of neuronal degeneration.

J Avendano, M M Rodrigues, J J Hackett, R Gaskins.   

Abstract

One hundred autopsy eyes were examined by light microscopy. Corpora amylacea (CA) occurred in 93% of the cases. Histochemical stains showed that these deposits are composed of sulfated polysaccharides. The fine structure of CA showed delicate, straight 6 to 7 nm thick filaments best demonstrated with the Thiery stain. In three cases, electron-dense vesicles resembling presynaptic vesicles were noted. These structures are characteristic of axons rather than of glial cells and could be related to protein synthesis. CA were present within myelinated and unmyelinated nerves and probably represent products of axonal degeneration.

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Year:  1980        PMID: 7189514

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  7 in total

Review 1.  Anatomic alterations in aging and age-related diseases of the eye.

Authors:  Hans E Grossniklaus; John M Nickerson; Henry F Edelhauser; Louise A M K Bergman; Lennart Berglin
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-12-13       Impact factor: 4.799

2.  Reduction in number of corpora amylacea with advancing histological changes of glaucoma.

Authors:  T Kubota; G O Naumann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1993-05       Impact factor: 3.117

3.  Intra-astrocytic glycogen granules and corpora amylacea stain positively for polyglucosans: a cytochemical contribution on the fine structural polymorphism of particulate polysaccharides.

Authors:  L Palmucci; A P Anzil; S Luh
Journal:  Acta Neuropathol       Date:  1982       Impact factor: 17.088

4.  Corpora amylacea in glaucomatous and non-glaucomatous optic nerve and retina.

Authors:  T Kubota; L M Holbach; G O Naumann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1993       Impact factor: 3.117

5.  Roughness of retinal layers in Alzheimer's disease.

Authors:  Lucía Jáñez-García; Omar Bachtoula; Elena Salobrar-García; Rosa de Hoz; Ana I Ramirez; Pedro Gil; José M Ramirez; Luis Jáñez-Escalada
Journal:  Sci Rep       Date:  2021-06-03       Impact factor: 4.379

6.  Corpora amylacea are associated with tau burden and cognitive status in Alzheimer's disease.

Authors:  Connor M Wander; Tamy Harumy Moraes Tsujimoto; John F Ervin; Chanung Wang; Spencer M Maranto; Vanya Bhat; Julian D Dallmeier; Shih-Hsiu Jerry Wang; Feng-Chang Lin; William K Scott; David M Holtzman; Todd J Cohen
Journal:  Acta Neuropathol Commun       Date:  2022-08-08       Impact factor: 7.578

7.  Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?

Authors:  Troy T Rohn
Journal:  Int J Neurol Neurother       Date:  2015-08-28
  7 in total

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