Literature DB >> 7188930

Twin studies and substrate differences in platelet monoamine oxidase activity.

L Hussein, E Sindarto, H W Goedde.   

Abstract

Monoamine oxidase activity was measured in blood platelets of 7 pairs of identical (MZ) twins and a similar number of age- and sex-matched control pairs. Mean intrapair difference in platelet MAO activity was significantly smaller (0.01 less than p less than 0.025) in MZ compared to controls. Kinetic studies of the enzyme revealed mean Km value of 1.0 x 10(-5) mol/l for tryptamine. Platelet MAO activity is higher in women than in men.

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Year:  1980        PMID: 7188930     DOI: 10.1159/000153104

Source DB:  PubMed          Journal:  Hum Hered        ISSN: 0001-5652            Impact factor:   0.444


  2 in total

1.  Platelet monoamine oxidase (MAO) activity: evidence for a single major locus.

Authors:  J Rice; P McGuffin; L R Goldin; E G Shaskan; E S Gershon
Journal:  Am J Hum Genet       Date:  1984-01       Impact factor: 11.025

Review 2.  Human platelet monoamine oxidase activity in health and disease: a review.

Authors:  M Sandler; M A Reveley; V Glover
Journal:  J Clin Pathol       Date:  1981-03       Impact factor: 3.411

  2 in total

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