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Literature DB >> 7188246

Inhibition of RNA viruses in vitro and in Rift Valley fever-infected mice by didemnins A and B.

P G Canonico, W L Pannier, J W Huggins, K L Rienehart.

Abstract

Didemnins, a new class of depsipeptides isolated from a Caribbean tunicate, have been shown to have potent antiviral activity against a broad range of RNA viruses in vitro. Didemnins A and B both protected mice against a lethal challenge of Rift Valley fever virus.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1982 PMID： 7188246 PMCID： PMC183817 DOI： 10.1128/AAC.22.4.696

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

1 in total

1. Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate.

Authors: K L Rinehart; J B Gloer; R G Hughes; H E Renis; J P McGovren; E B Swynenberg; D A Stringfellow; S L Kuentzel; L H Li
Journal: Science Date: 1981-05-22 Impact factor: 47.728

1 in total

5 in total

Review 1. Didemnin B. The first marine compound entering clinical trials as an antineoplastic agent.

Authors: H G Chun; B Davies; D Hoth; M Suffness; J Plowman; K Flora; C Grieshaber; B Leyland-Jones
Journal: Invest New Drugs Date: 1986 Impact factor: 3.850

Review 2. Potential "biopeptidal" therapeutics for severe respiratory syndrome coronaviruses: a review of antiviral peptides, viral mechanisms, and prospective needs.

Authors: Tolulope Joshua Ashaolu; Asad Nawaz; Noman Walayat; Ibrahim Khalifa
Journal: Appl Microbiol Biotechnol Date: 2021-04-19 Impact factor: 4.813

Inhibition of RNA viruses in vitro and in Rift Valley fever-infected mice by didemnins A and B.

1. Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate.

Review 1. Didemnin B. The first marine compound entering clinical trials as an antineoplastic agent.

Review 2. Potential "biopeptidal" therapeutics for severe respiratory syndrome coronaviruses: a review of antiviral peptides, viral mechanisms, and prospective needs.

Review 3. Promising bioactive compounds from the marine environment and their potential effects on various diseases.

Review 4. Marine Natural Products from Tunicates and Their Associated Microbes.

Review 5. Marine natural products and their potential applications as anti-infective agents.