Literature DB >> 71861

The binding of chloroquine to normal and Kwashiorkor serum.

N Buchanan, L A Van der Walt.   

Abstract

The binding of chloroquine to kwashiorkor and normal serum was investigated. The results show that more drug is bound in kwashiorkor serum, and that this occurs predominantly at the gamma globulin fraction. Therapeutically, in malnutrition there is no significant abnormality of protein binding with respect to chloroquine.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 71861     DOI: 10.4269/ajtmh.1977.26.1025

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  7 in total

1.  Pharmacokinetics of chloroquine: saliva and plasma levels relationship.

Authors:  E I Ette; E E Essien; E E Brown-Awala
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1986 Oct-Dec       Impact factor: 2.441

Review 2.  Clinical pharmacokinetics and metabolism of chloroquine. Focus on recent advancements.

Authors:  J Ducharme; R Farinotti
Journal:  Clin Pharmacokinet       Date:  1996-10       Impact factor: 6.447

3.  Protein binding of chloroquine in the presence of aspirin.

Authors:  S A Adelusi; L A Salako
Journal:  Br J Clin Pharmacol       Date:  1982-03       Impact factor: 4.335

Review 4.  A systematic review of pharmacokinetics studies in children with protein-energy malnutrition.

Authors:  Kazeem A Oshikoya; Helen M Sammons; Imti Choonara
Journal:  Eur J Clin Pharmacol       Date:  2010-06-16       Impact factor: 2.953

Review 5.  Clinical pharmacokinetics of antimalarial drugs.

Authors:  N J White
Journal:  Clin Pharmacokinet       Date:  1985 May-Jun       Impact factor: 6.447

6.  Characterization of chloroquine plasma protein binding in man.

Authors:  O Walker; D J Birkett; G Alván; L L Gustafsson; F Sjöqvist
Journal:  Br J Clin Pharmacol       Date:  1983-03       Impact factor: 4.335

7.  Pathophysiological changes that affect drug disposition in protein-energy malnourished children.

Authors:  Kazeem A Oshikoya; Idowu O Senbanjo
Journal:  Nutr Metab (Lond)       Date:  2009-12-01       Impact factor: 4.169

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.