Literature DB >> 7185255

On the cytoprotective action of sulfhydryl-containing substances.

G A Bálint, V Varró.   

Abstract

Sulfhydryl substances (cysteine, glutathione, cysteamine and BAL) provide protection against experimental gastric ulcer induced by indomethacin while being ulcerogenous in stress-ulcer. Experimental data indicate the necessity to distinguish between "real" and "occasional" cytoprotective drugs.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 7185255

Source DB:  PubMed          Journal:  Acta Physiol Acad Sci Hung        ISSN： 0001-6756


  6 in total

1.  Gastrointestinal mucosal gamma-glutamyl transpeptidase activity changes in different ulcer models of rat.

Authors:  J Náfrádi; G A Balint; S Csáti; V Varró
Journal:  Agents Actions       Date:  1984-12

2.  The effect of long-term prostacyclin treatment on the protein, DNA and RNA content of rat gastric fundic mucosa.

Authors:  G A Balint; G Karácsony; V Varró
Journal:  Agents Actions       Date:  1985-07

3.  Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo.

Authors:  M Romano; W H Polk; J A Awad; C L Arteaga; L B Nanney; M J Wargovich; E R Kraus; C R Boland; R J Coffey
Journal:  J Clin Invest       Date:  1992-12       Impact factor: 14.808

4.  Protein and non-protein sulfhydryls and disulfides in gastric mucosa and liver after gastrotoxic chemicals and sucralfate: possible new targets of pharmacologic agents.

Authors:  Lajos Nagy; Miki Nagata; Sandor Szabo
Journal:  World J Gastroenterol       Date:  2007-04-14       Impact factor: 5.742

5.  Intragastric nicotine protects against 40% ethanol-induced gastric mucosal injury despite pretreatment with propranolol or N-ethylmaleimide in rats.

Authors:  K Endoh; G Ro; F W Leung
Journal:  Dig Dis Sci       Date:  1992-03       Impact factor: 3.199

6.  Cysteamine protects gastric epithelial cell monolayers against drug induced damage: evidence for direct cellular protection by sulphydryl compounds.

Authors:  M Romano; M Razandi; A Raza; S Szabo; J Ivey
Journal:  Gut       Date:  1992-01       Impact factor: 23.059
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.