Literature DB >> 7184998

Repetitive doses of activated charcoal in Dapsone poisoning in a child.

J R Reigart, H L Trammel, J M Lindsey.   

Abstract

A case of Dapsone poisoning, treated by repetitive dosing with activated charcoal, is reported. This 18-month-old child showed remarkably rapid resolution of his symptoms with this mode of therapy, becoming symptom free in 64 h. This rapid improvement is attributed to interruption by activated charcoal of the enterohepatic circulation of Dapsone. This mode of therapy may be indicated for other compounds having an enterohepatic circulation.

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Year:  1982        PMID： 7184998     DOI： 10.3109/15563658208992541

Source DB:  PubMed          Journal:  J Toxicol Clin Toxicol        ISSN： 0731-3810


  4 in total

1.  Management of dapsone poisoning complicated by methaemoglobinaemia.

Authors:  A H Dawson; I M Whyte
Journal:  Med Toxicol Adverse Drug Exp       Date:  1989 Sep-Oct

Review 2.  Activated charcoal--past, present and future.

Authors:  R W Derlet; T E Albertson
Journal:  West J Med       Date:  1986-10

Review 3.  Clinical features and management of poisoning due to antimalarial drugs.

Authors:  A Jaeger; P Sauder; J Kopferschmitt; F Flesch
Journal:  Med Toxicol Adverse Drug Exp       Date:  1987 Jul-Aug

Review 4.  Oral activated charcoal in the treatment of intoxications. Role of single and repeated doses.

Authors:  P J Neuvonen; K T Olkkola
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Jan-Dec
  4 in total

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