Literature DB >> 7181481

Immunological responsiveness of guinea pigs to antibiotics diffusing from bone cement.

B H Petersen, L A Steimel, H R Black.   

Abstract

The sustained release of antibiotics from bone cement provides an opportunity for the induction of hypersensitivity. We evaluated the cellular and humoral immune responsiveness of guinea pigs to antibiotics diffusing from bone cement. We were unable to detect the presence of antibodies or skin hypersensitivity to any of the antibiotics tested.

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Year:  1982        PMID: 7181481      PMCID: PMC183820          DOI: 10.1128/AAC.22.4.704

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  4 in total

1.  Immunologic cross-reactivity of cephalexin and penicillin.

Authors:  B H Petersen; J Graham
Journal:  J Lab Clin Med       Date:  1974-06

2.  Letter: Antibiotic-bone-cement mixtures in prevention of infection following total joint replacement.

Authors:  A D Gardner; J W Medcraft
Journal:  Lancet       Date:  1974-10-12       Impact factor: 79.321

3.  Cephalosporins in bone cement: studies in vitro and in vivo.

Authors:  S Hughes; C A Field; M R Kennedy; C H Dash
Journal:  J Bone Joint Surg Br       Date:  1979-02

Review 4.  Immunological tolerance.

Authors:  J G Howard; N A Mitchison
Journal:  Prog Allergy       Date:  1975
  4 in total

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