Literature DB >> 7179849

[Oncologic properties of non-inbred white rats raised at the Petrov Research Institute of the Ministry of Health of the USSR].

G B Pliss, M G Iogannsen, A N Romanov, K P Romanov.   

Abstract

The paper discusses the incidence of spontaneous tumors and general morbidity in albino noninbred rats raised at the N. N. Petrov Research Institute of Oncology of the USSR Ministry of Health and used in different chronic experiments. It was found that spontaneous tumors occur, on the average, in 25.7 and malignancies--in 6.2%. Infectious hemorrhagic pneumonia and gastroenteritis (acute capillary toxicosis) are relatively infrequent. The general morbidity patterns in these rats are similar to those in Wistar line, the essential difference being a lower frequency of tumors of the medullar layer of adrenals. Hence, the rats bred at the Institute may be successfully used in various chronic experiments, including those associated with carcinogenic studies.

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Year:  1982        PMID: 7179849

Source DB:  PubMed          Journal:  Vopr Onkol        ISSN: 0507-3758


  2 in total

1.  Possibility of inducing glandular stomach cancer in rats exposed to asbestos.

Authors:  F M Kogan; N N Vanchugova; V N Frasch
Journal:  Br J Ind Med       Date:  1987-10

2.  Effect of age on dose-response relationship in carcinogenesis induced by single administration of N-nitrosomethylurea in female rats.

Authors:  V N Anisimov
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553

  2 in total

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