Effect on the incidence of atrophic rhinitis of vaccination of sows with a vaccine containing Pasteurella multocida toxin.

Combined experimental infections with Bordetella bronchiseptica and either a toxigenic or a non-toxic strain of P. multocida were carried out in newborn specific pathogen free piglets born to 25 sows. Pigs inoculated with B. bronchiseptica and toxin-producing P. multocida developed severe progressive atrophic rhinitis corresponding to the natural disease. The effect of vaccination of sows with a toxin-containing P. multocida vaccine on the incidence of nasal lesions in the offspring was studied.