Literature DB >> 7175529

Deficient catecholamine release as the basis of orthostatic hypotension in pernicious anaemia.

G Eisenhofer, D G Lambie, R H Johnson, E Tan, E A Whiteside.   

Abstract

A patient with peripheral neuropathy and orthostatic hypotension was found to have pernicious anaemia. Symptoms improved after vitamin B12 replacement therapy. Insulin tolerance testing showed that the patient lacked catecholamine, heart rate, and sweating responses to hypoglycaemia. This indicates that pernicious anaemia may cause orthostatic hypotension owing to failure of noradrenaline release.

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Year:  1982        PMID： 7175529      PMCID： PMC491645          DOI： 10.1136/jnnp.45.11.1053

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  10 in total

1.  Shy-Drager syndrome with abnormal respirations and antidiuretic hormone release.

Authors:  A H Lockwood
Journal:  Arch Neurol       Date:  1976-04

2.  Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.

Authors:  J D Peuler; G A Johnson
Journal:  Life Sci       Date:  1977-09-01       Impact factor: 5.037

Review 3.  Disorders of the autonomic nervous system. Chapter 6. Arterial hypotension.

Authors:  R H Johnson; J M Spaulding
Journal:  Contemp Neurol Ser       Date:  1974

4.  Peripheral nerve function in vitamin B 12 deficiency.

Authors:  R F Mayer
Journal:  Arch Neurol       Date:  1965-10

5.  [Spinal cord diseases and vitamin B l2 deficiency psychosis].

Authors:  H H Wieck
Journal:  Med Klin       Date:  1967-05-12

6.  Plasma catecholamines in diabetes. The syndromes of hypoadrenergic and hyperadrenergic postural hypotension.

Authors:  P E Cryer; A B Silverberg; J V Santiago; S D Shah
Journal:  Am J Med       Date:  1978-03       Impact factor: 4.965

7.  Hormonal responses to hypoglycemia in orthostatic hypotension patients with adrenergic insufficiency.

Authors:  R J Polinsky; I J Kopin; M H Ebert; V Weise; L Recant
Journal:  Life Sci       Date:  1981-07-27       Impact factor: 5.037

8.  The sympathetic-nervous-system defect in primary orthostatic hypotension.

Authors:  M G Ziegler; C R Lake; I J Kopin
Journal:  N Engl J Med       Date:  1977-02-10       Impact factor: 91.245

9.  Basis of nocturnal polyuria in patients with autonomic failure.

Authors:  C S Wilcox; M J Aminoff; W Penn
Journal:  J Neurol Neurosurg Psychiatry       Date:  1974-06       Impact factor: 10.154

10.  Pernicious anemia seen initially as orthostatic hypotension.

Authors:  W B White; L Reik; D E Cutlip
Journal:  Arch Intern Med       Date:  1981-10
  10 in total
  4 in total

1.  Orthostatic hypotension in organic dementia: relationship between blood pressure, cortical blood flow and symptoms.

Authors:  U Passant; S Warkentin; S Karlson; K Nilsson; L Edvinsson; L Gustafson
Journal:  Clin Auton Res       Date:  1996-02       Impact factor: 4.435

2.  Megaloblastic anemia with hypotension and transient delirium as the primary symptoms: report of a case.

Authors:  Qin Zhang; Xue-Ying Lv; Yun-Mei Yang
Journal:  Int J Clin Exp Med       Date:  2015-10-15

3.  B12 deficiency with neurological manifestations in the absence of anaemia.

Authors:  Dissanayake Mudiyanselage Priyantha Udaya Kumara Ralapanawa; Kushalee Poornima Jayawickreme; Ekanayake Mudiyanselage Madhushanka Ekanayake; Widana Arachchilage Thilak Ananda Jayalath
Journal:  BMC Res Notes       Date:  2015-09-18

4.  An Impaired Awareness of Hypoglycemia Improved After Vitamin B12 Treatment in a Type 1 Diabetic Patient.

Authors:  Shingo Fujita; Junji Kozawa; Chisaki Ishibashi; Takekazu Kimura; Tetsuhiro Kitamura; Kenji Fukui; Tetsuyuki Yasuda; Hiromi Iwahashi; Akihisa Imagawa; Iichiro Shimomura
Journal:  Intern Med       Date:  2017-06-01       Impact factor: 1.271
  4 in total

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