Lack of correlation of postmortem vitreous humor calcium concentration with antemortem serum calcium concentration.

Although results of several studies measuring calcium concentrations in vitreous humor have been published, comparisons of postmortem vitreous calcium with antemortem serum calcium have not been made. In a study of 30 cases in which antemortem calcium results were available, the mean vitreous calcium concentration was 6.8 mg/dL. There was no significant change in vitreous calcium postmortem nor significant correlation between vitreous calcium and antemortem serum calcium. Experimental observations suggest that vitreous calcium is regulated by an active transport mechanism. Vitreous calcium measurements do not appear to be useful in evaluating suspected antemortem abnormalities of serum calcium.