Literature DB >> 717400

Average heterozygosity revisited.

P W Hedrick, E Murray.   

Abstract

The estimate of heterozygosity and proportion of polymorphic loci for 33 red blood cell loci has been updated by the elimination of some loci of questionable status and the addition of data on 33 loci. The new figures for heterozygosity and proportion of polymorphic loci, .105 and .283, respectively, are based on 60 red blood cell loci of European origin populations. These values are less than those calculated by Lewontin in 1967, and furthermore they do not appear to be reaching an asymptote. At the present time, the red blood cell data and allozyme data for European populations have similar estimates of heterozygosity and proportion of polymorphic loci.

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Year:  1978        PMID: 717400      PMCID: PMC1685618     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN: 0002-9297            Impact factor:   11.025


  4 in total

1.  Evidence that enzyme polymorphisms are selectively neutral, but blood group polymorphisms are not.

Authors:  T Yamazaki; T Maruyama
Journal:  Science       Date:  1974-03-15       Impact factor: 47.728

2.  Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphisms.

Authors:  H Harris; D A Hopkinson
Journal:  Ann Hum Genet       Date:  1972-07       Impact factor: 1.670

3.  An estimate of average heterozygosity in man.

Authors:  R C Lewontin
Journal:  Am J Hum Genet       Date:  1967-09       Impact factor: 11.025

4.  Genetic heterogeneity within electrophoretic "alleles" of xanthine dehydrogenase in Drosophila pseudoobscura.

Authors:  R S Singh; R C Lewontin; A A Felton
Journal:  Genetics       Date:  1976-11       Impact factor: 4.562

  4 in total
  1 in total

1.  Heterozygosity levels in a mammal: A determination derived from allele frequencies at loci controlling gross morphology.

Authors:  B Blumenberg
Journal:  Theor Appl Genet       Date:  1980-07       Impact factor: 5.699

  1 in total

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