| Literature DB >> 7173951 |
Abstract
Subcultures of smooth muscle cells derived from rat thoracic aorta were grown on plane plastic substrata and on plastic substrata having ridges molded in them by a heated, ruled template. The cells were found to have a very high degree of contact guidance when distributed sparsely on the ridged substrata. When the cell density increased multilayered, elongated colonies formed. On plane substrata these were irregular, curved, and disposed in all directions. On the ridged substrata, however, the colonies were straight, evenly spaced, and positioned at right angles to the ridges.Entities:
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Year: 1982 PMID: 7173951 DOI: 10.1007/bf02796502
Source DB: PubMed Journal: In Vitro ISSN: 0073-5655