Literature DB >> 7171128

Sorbitol dehydrogenase genetics in the mouse: a 'null' mutant in a 'European' C57BL strain.

R S Holmes, J A Duley, J Hilgers.   

Abstract

A 'null' activity variant phenotype for sorbitol dehydrogenase (SDH) was observed in C57BL/LiA mice and used to examine the genetics of this enzyme. Linkage studies of the locus (Sdh-1) with non-agouti (a) and a biochemical locus encoding liver L-alpha-hydroxyacid oxidase (Hao-1) demonstrated that it is coincident with or closely linked to the structural locus, previously localized on chromosome 2. Alcohol dehydrogenase (ADH) isozymes were also examined, since the liver A2 isozyme exhibited some activity as a sorbitol dehydrogenase on cellulose acetate zymograms. It is apparent that SDH activity is not 'essential' in this mouse strain.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 7171128     DOI： 10.1111/j.1365-2052.1982.tb01569.x

Source DB:  PubMed          Journal:  Anim Blood Groups Biochem Genet        ISSN： 0003-3480


  7 in total

Review 1.  Mouse map of paralogous genes.

Authors:  J H Nadeau; M Kosowsky
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

2.  Organic aciduria and butyryl CoA dehydrogenase deficiency in BALB/cByJ mice.

Authors:  S P Schiffer; M Prochazka; P F Jezyk; T H Roderick; M Yudkoff; D F Patterson
Journal:  Biochem Genet       Date:  1989-02       Impact factor: 1.890

3.  Effects of Averrhoa carambola L. (Oxalidaceae) juice mediated on hyperglycemia, hyperlipidemia, and its influence on regulatory protein expression in the injured kidneys of streptozotocin-induced diabetic mice.

Authors:  Hoa Thi Thai Pham; Wansu Huang; Chuangye Han; Juman Li; Qiuqiao Xie; Jinbin Wei; Xiaohui Xu; Zefeng Lai; Xiang Huang; Renbin Huang; Qingwei Wen
Journal:  Am J Transl Res       Date:  2017-01-15       Impact factor: 4.060

4.  Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.

Authors:  A Y Lee; S K Chung; S S Chung
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205

5.  Sorbitol can fuel mouse sperm motility and protein tyrosine phosphorylation via sorbitol dehydrogenase.

Authors:  Wenlei Cao; Haig K Aghajanian; Lisa A Haig-Ladewig; George L Gerton
Journal:  Biol Reprod       Date:  2008-09-17       Impact factor: 4.285

6.  Redox state-dependent and sorbitol accumulation-independent diabetic albuminuria in mice with transgene-derived human aldose reductase and sorbitol dehydrogenase deficiency.

Authors:  S Ii; M Ohta; E Kudo; T Yamaoka; T Tachikawa; M Moritani; M Itakura; K Yoshimoto
Journal:  Diabetologia       Date:  2004-02-14       Impact factor: 10.122

7.  Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes.

Authors:  Andrea Cortese; Yi Zhu; Adriana P Rebelo; Sara Negri; Steve Courel; Lisa Abreu; Chelsea J Bacon; Yunhong Bai; Dana M Bis-Brewer; Enrico Bugiardini; Elena Buglo; Matt C Danzi; Shawna M E Feely; Alkyoni Athanasiou-Fragkouli; Nourelhoda A Haridy; Rosario Isasi; Alaa Khan; Matilde Laurà; Stefania Magri; Menelaos Pipis; Chiara Pisciotta; Eric Powell; Alexander M Rossor; Paola Saveri; Janet E Sowden; Stefano Tozza; Jana Vandrovcova; Julia Dallman; Elena Grignani; Enrico Marchioni; Steven S Scherer; Beisha Tang; Zhiqiang Lin; Abdullah Al-Ajmi; Rebecca Schüle; Matthis Synofzik; Thierry Maisonobe; Tanya Stojkovic; Michaela Auer-Grumbach; Mohamed A Abdelhamed; Sherifa A Hamed; Ruxu Zhang; Fiore Manganelli; Lucio Santoro; Franco Taroni; Davide Pareyson; Henry Houlden; David N Herrmann; Mary M Reilly; Michael E Shy; R Grace Zhai; Stephan Zuchner
Journal:  Nat Genet       Date:  2020-05-04       Impact factor: 41.307
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.