Literature DB >> 7168730

Rapid forgetting in aged rats.

S F Zornetzer, R Thompson, J Rogers.   

Abstract

The retention performance of young (3-6 months) and aged (24-26 months) Sprague-Dawley rats was evaluated on three separate experimental paradigms. The three paradigms were sequenced so that the first, spontaneous alternation, tested for retention performance of short-term memory; the second, step-down inhibitory (passive) avoidance, tested for long-term memory; while the third, a shock-motivated spatial reversal problem, tested for both short- and long-term memory. The results suggest that aged rats experience significantly more rapid forgetting in both short- and long-term memory systems.

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Mesh:

Year:  1982        PMID: 7168730     DOI: 10.1016/s0163-1047(82)90234-5

Source DB:  PubMed          Journal:  Behav Neural Biol        ISSN: 0163-1047


  19 in total

1.  Testosterone impairs the acquisition of an operant delayed alternation task in male rats.

Authors:  Steven L Neese; Susan L Schantz
Journal:  Horm Behav       Date:  2011-10-25       Impact factor: 3.587

2.  Aging and stress: past hypotheses, present approaches and perspectives.

Authors:  Pedro Garrido
Journal:  Aging Dis       Date:  2011-01-28       Impact factor: 6.745

Review 3.  Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-D-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticity.

Authors:  Thomas C Foster
Journal:  Prog Neurobiol       Date:  2012-01-28       Impact factor: 11.685

4.  Effect of Panax ginseng extract on passive avoidance retention in old rats.

Authors:  B Jaenicke; E J Kim; J W Ahn; H S Lee
Journal:  Arch Pharm Res       Date:  1991-03       Impact factor: 4.946

5.  Susceptibility to induction of long-term depression is associated with impaired memory in aged Fischer 344 rats.

Authors:  Thomas C Foster; Ashok Kumar
Journal:  Neurobiol Learn Mem       Date:  2007-02-05       Impact factor: 2.877

6.  Age-related impairments in memory and in CREB and pCREB expression in hippocampus and amygdala following inhibitory avoidance training.

Authors:  Ken A Morris; Paul E Gold
Journal:  Mech Ageing Dev       Date:  2012-03-16       Impact factor: 5.432

7.  Effects of multiple daily genistein treatments on delayed alternation and a differential reinforcement of low rates of responding task in middle-aged rats.

Authors:  Steven L Neese; Suren B Bandara; Daniel R Doerge; William G Helferich; Donna L Korol; Susan L Schantz
Journal:  Neurotoxicol Teratol       Date:  2011-09-14       Impact factor: 3.763

8.  Voluntary exercise impairs initial delayed spatial alternation performance in estradiol treated ovariectomized middle-aged rats.

Authors:  Steven L Neese; Donna L Korol; Susan L Schantz
Journal:  Horm Behav       Date:  2013-09-03       Impact factor: 3.587

Review 9.  Forgetfulness during aging: an integrated biology.

Authors:  Paul E Gold; Donna L Korol
Journal:  Neurobiol Learn Mem       Date:  2014-03-24       Impact factor: 2.877

10.  Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging.

Authors:  Sarah M Neuner; Benjamin P Garfinkel; Lynda A Wilmott; Bogna M Ignatowska-Jankowska; Ami Citri; Joseph Orly; Lu Lu; Rupert W Overall; Megan K Mulligan; Gerd Kempermann; Robert W Williams; Kristen M S O'Connell; Catherine C Kaczorowski
Journal:  Neurobiol Aging       Date:  2016-06-17       Impact factor: 4.673

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