Literature DB >> 7167415

The effect of prostaglandins on climbing behavior induced by apomorphine in mice.

R Brus, Z Kruk, M Wesołowska, B Stanosek.   

Abstract

Prostaglandins E2, F2 alpha, D2 and I2 administered intracerebroventricularly in a dose of 1 microgram, inhibited the climbing behavior induced by apomorphine. The most active in this respect was PGE2, the least--PGD2. The results indicate the participation of prostaglandins in the regulation of central dopaminergic function.

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Year:  1982        PMID: 7167415

Source DB:  PubMed          Journal:  Pol J Pharmacol Pharm        ISSN: 0301-0244


  1 in total

1.  Modification of dyskinesias following the intrastriatal injection of prostaglandins in the rodent.

Authors:  B Costall; S W Holmes; M E Kelly; R J Naylor
Journal:  Br J Pharmacol       Date:  1985-08       Impact factor: 8.739

  1 in total

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