| Literature DB >> 7166915 |
H Yamagishi, H Ishibashi, M Kodama, T Tanaka, Y Harada, I Hashimoto.
Abstract
A patient with an abdominal tumor and gastric cancer was treated with intraperitoneal OK-432 alone. Her general condition improved and the abdominal mass diminished significantly. The fluoroscopic radiography and gastroduodenal fiberscopic examinations revealed a slight improvement. Four months after the initiation of OK-432 therapy, microscopic examination of the biopsy specimen disclosed degenerated tumor cells with a pronounced accumulation of lymphocytes and large monocytes which were ascertained to be macrophages by the fluorescent antibody technique using anti-macrophage serum. This study revealed one possible mechanism of the antitumor action of OK-432.Entities:
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Year: 1982 PMID： 7166915 DOI： 10.1007/bf02469834
Source DB: PubMed Journal: Jpn J Surg ISSN： 0047-1909