| Literature DB >> 7165348 |
Abstract
A tentative model is presented which is based on existing published data. The model suggests that the epidermal Langerhans cell plays a central role in contact dermatitis by proliferation control of keratinocytes and as the most peripheral outpost of the immune system. Contact dermatitis to chemicals is the injurious expression of a defense mechanism designed phylogenetically against arthropods and insects.Entities:
Mesh:
Year: 1982 PMID: 7165348 DOI: 10.1007/bf00509072
Source DB: PubMed Journal: Arch Dermatol Res ISSN: 0340-3696 Impact factor: 3.017