Literature DB >> 7165121

Copper iontophoresis in male contraception.

S S Riar, R C Sawhney, J Bardhan, P Thomas, R K Jain, A K Kain.   

Abstract

Copper was deposited by iontophoresis into vasa deferentia of animals, using 1 m. amp. current for 30-90 sec. in rat and 3 m. amp. current for 60 sec. in rabbits. The method was effective for a period of 9 months as a contraceptive. The effect of the metal was localised at the site of deposition and there was no effect on other reproductive organs. The mating behaviour and testosterone levels did not change. The utility of the technique in male contraception is discussed.

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Keywords:  Animals, Laboratory; Biology; Clinical Research; Contraception; Contraception Research; Copper; Family Planning; Genitalia; Germ Cells; Ingredients And Chemicals; Inorganic Chemicals; Male Contraception; Metals; Physiology; Research Methodology; Spermatozoa; Urogenital System

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Year:  1982        PMID: 7165121     DOI: 10.1111/j.1439-0272.1982.tb02298.x

Source DB:  PubMed          Journal:  Andrologia        ISSN: 0303-4569            Impact factor:   2.775


  1 in total

1.  lontophoretic Devices for Drug Delivery.

Authors:  P Tyle
Journal:  Pharm Res       Date:  1986-12       Impact factor: 4.200

  1 in total

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